Microemulsions are optically transparent,
homogeneous and low viscous properties; compose of
water phase, oil phase and surfactant/co-surfactant
mixture (Smix) to stabilize system. Microemulsions
forms spontaneously with an average droplet diameter
of 10 to 140 nm (Cross et al,. 2008). Microemulsions
can be applies as enhance penetration through the skin
by transport lipophilic substance through an aqueous
medium or to carry hydrophilic substance across
lipophilic medium [4]. Advantages of microemulsions
are good thermodynamic stability, ease of
manufacturing, spontaneous formation and enhance
delivery drugs via several routes. Recently,
microemulsions have used wildly several applications in
cosmetics.
Therefore, tea tree oil was subjected to construct
microemulsions. The formulation with different mass
ratio of surfactant to co-surfactant (Smix) of 1:1, 2:1
and 3:1 were determined. After that, microemulsion
obtained from pseudo-ternary phase diagram was
depicted for characteristic analysis