The JH effect on Bmdimm was mediated by the JH-MetKr-h1signalingpathway,andBmdimmexpressiondidnotrespond to JH by RNA interference with double-stranded BmKr-h1 RNA. These data suggest that the JH regulatory pathway, the transcriptionfactorBmdimm,andthetargetedfib-Hgenecontributetothe synthesis of fibroin H-chain protein in B. mori.