Davis et al. (2008) found that hepatic GHR1 and GHR2 expressions
were higher in male than in female (Davis et al., 2008). However, the
study only focused on the expression differences between males and
females while the mechanisms of this phenomenonwere not discussed.
In the present study, we indicated that the expression difference of GH
in the pituitary between males and females results from the different
methylation levels which contribute to the connection between epigenetic
and genetic in tilapia.