Exposure
The containers for the printing colors were cleaned by
hand with pure toluene. The room was small and had poor
ventilation. The door and the window were usually kept
closed due to low winter temperatures. Exposure was determined
by personal air sampling with adsorption on charcoal
tubes, desorption with benzylic alcohol, and headspace gas
chromatography. Venous blood samples were taken immediately
before and after cleaning, and toluene was determined
by gas chromatography. Ethanol in blood samples of exposed
workers and of controls, taken before testing, was determined
enzymatically with alcohol dehydrogenase (Sigma, Germany).
None of the workers or of the controls drank alcohol before
or during the experiment. Subjects were watched during the
whole procedure. We had intended to perform the cleaning at
the beginning of the shift when blood concentrations of toluene
were low, but this was not possible in most cases due to
the working process.
Exposure
The containers for the printing colors were cleaned by
hand with pure toluene. The room was small and had poor
ventilation. The door and the window were usually kept
closed due to low winter temperatures. Exposure was determined
by personal air sampling with adsorption on charcoal
tubes, desorption with benzylic alcohol, and headspace gas
chromatography. Venous blood samples were taken immediately
before and after cleaning, and toluene was determined
by gas chromatography. Ethanol in blood samples of exposed
workers and of controls, taken before testing, was determined
enzymatically with alcohol dehydrogenase (Sigma, Germany).
None of the workers or of the controls drank alcohol before
or during the experiment. Subjects were watched during the
whole procedure. We had intended to perform the cleaning at
the beginning of the shift when blood concentrations of toluene
were low, but this was not possible in most cases due to
the working process.
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