An important mechanism in inflammation is the recruitment of macrophages and the released of interleukins, such as IL-1 which induces the expression of the COXgene. Flavonoids can inhibit the production of eicosanoids, formed from arachidonic acid by a series of enzymes, particularly PG COX, having also an important effect on the intricate regulatory processes of cardiovascular diseases and markedly improving the condition of patients suffering
from these progressive illnesses (Havsteen, 2002). The results of many anti-inflammatory experiments involving Capsicum species extracts, including Capsicum baccatum, have suggested, but not proved, that capsaicin might be the major compound responsible for the observed anti-inflammatory effects