Sixty-four specimens were studied in both retrospective
and prospective manner. This study was reviewed and
approved by the Institutional Review Board of The Houston
Methodist Hospital, Research Institute, Houston, TX. These
cases were categorized into 3 groups.
Group 1 included 26 cases with abundant amyloid
deposition, in which the identification of amyloid was
straightforward, even by routine hematoxylin and eosin
(H&E) stain;thisgroup included6 heart specimens (3explants
and 3 biopsies); 5 liver specimens (4 biopsies and 1 explant);
3 kidney biopsies; 3 corneal excisions; 2 small bowel biopsies;
2 pancreatectomy specimens; and 5 excisional biopsies of
thyroid, urinary bladder, lymph node, vocal cord, and lung
(one of each).
Sixty-four specimens were studied in both retrospective
and prospective manner. This study was reviewed and
approved by the Institutional Review Board of The Houston
Methodist Hospital, Research Institute, Houston, TX. These
cases were categorized into 3 groups.
Group 1 included 26 cases with abundant amyloid
deposition, in which the identification of amyloid was
straightforward, even by routine hematoxylin and eosin
(H&E) stain;thisgroup included6 heart specimens (3explants
and 3 biopsies); 5 liver specimens (4 biopsies and 1 explant);
3 kidney biopsies; 3 corneal excisions; 2 small bowel biopsies;
2 pancreatectomy specimens; and 5 excisional biopsies of
thyroid, urinary bladder, lymph node, vocal cord, and lung
(one of each).
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