13,394 patients, comparing either a statin vs. placebo or high-dose vs. moderate-dose statin therapy [24]. All statins were administered once daily and the odds ratio of new-onset T2DM was adjusted for percent- age of LDL-C reduction as a covariate. When compared with placebo, the risk for T2DM was greater for 20 mg daily rosuvastatin (+25%), and decreased with other statins to + 21% (40 mg simvastatin), + 15% (80 mg atorvastatin) and + 7% (40 mg pravastatin).