Comprehensive understanding of the signs, symptoms,
and pathogenesis of PUP requires an experienced medical
management team with knowledge of indicators associated
with PUP.
Currently, there is no gold standard for diagnosis of PUP
and there is limited data regarding diagnostic indicators for
early detection of PUP among patients in Thailand. The aim
of this study was to determine specific diagnostic indicators
of PUP based on patients’ personal habits, physical examination,
signs and symptoms, laboratory investigations, radiological
finding, and treatment role, which would be useful
for doctors and nurses in emergency or surgical departments.
These indicators would establish prompt diagnosis in order
to reduce PUP and risk of death from delayed treatment.5,7,12
Diagnostic indicators of PUP are needed for early detection
among patients undergoing perforation in order to improve
clinical outcome.