4. Conclusion
In this paper, a novel, efficient and nano-sized BPA-imprinted
silica sorbent was synthesized by a surface imprinting technique.
The BPA-imprinted silica nanoparticles showed high adsorption
capacity and selectivity, and offered a fast kinetics for the rebinding
of BPA. The MIP-SPE and HPLC method showed more efficient
clean-up of BPA from shampoo, bath lotion and cosmetic cream
samples than traditional C18-SPE and HPLC method. Also the MIPSPE
and HPLC method could provide satisfactory recoveries and
reproducibility.
It has clearly indicated that the combination of nanotechnique
with molecular imprinting technique can significantly improve the
binding capacity and kinetics. Although the current work is mainly
focused on the imprinting of BPA molecules, the experimental
results demonstrate that the silica nanostructure with imprinting
technique is an ideal approach for the imprinting of various organic
or biological molecules. It is competent to be exploited in concentration
and purification of trace analytes in the complex matrix.