If your cholesterol levels are not under control, you are at higher risk of heart disease. Your doctor may prescribe a common statin drug called simvastatin to lower your cholesterol, and you may be able to further reduce your risk of heart disease by taking fish oil, which may lower levels of triglycerides in your blood and promote a healthy blood pressure, according to MayoClinic.com. In some cases, you can safely take fish oil with simvastatin before bed; consult with your doctor as to whether this course is appropriate for you