Acute Controlled Exposure Human Studies. Several published studies of respiratory function and/or irritation of the nose, eyes, and throat are available involving acute controlled exposure of volunteers, generally at formaldehyde concentrations ≤3 ppm. Reviews of these studies include those by Arts et al. (2006a, 2006b) and Lang, 2008. Controlled exposure human studies have found that short-term inhalation exposures to concentrations ranging from 0.4 to 3 ppm can produce symptoms of mild to moderate irritation of the eyes, nose, and throat. The odor threshold for formaldehyde in humans has been reported to be 1 ppm (Leonardos et al. 1969), but others have noted that it may range as low as
0.05 ppm (Arts et al. 2006a).
Acute Controlled Exposure Human Studies. Several published studies of respiratory function and/or irritation of the nose, eyes, and throat are available involving acute controlled exposure of volunteers, generally at formaldehyde concentrations ≤3 ppm. Reviews of these studies include those by Arts et al. (2006a, 2006b) and Lang, 2008. Controlled exposure human studies have found that short-term inhalation exposures to concentrations ranging from 0.4 to 3 ppm can produce symptoms of mild to moderate irritation of the eyes, nose, and throat. The odor threshold for formaldehyde in humans has been reported to be 1 ppm (Leonardos et al. 1969), but others have noted that it may range as low as0.05 ppm (Arts et al. 2006a).
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