This review is to examine the current literatures on the relationship between periodontitis and hypertension as well as to explore the
possible biological pathways underlying the linkage between these health conditions. Hypertension is one of the major risk factors
for cardiovascular diseases. Oxidative stress and endothelial dysfunction are among the critical components in the development
of hypertension. Inflammation has received much attention recently and may contribute to a pivotal role in hypertension.
Periodontitis, a chronic low-grade inflammation of gingival tissue, has been linked to endothelial dysfunction, with blood pressure
elevation and increased mortality risk in hypertensive patients. Inflammatory biomarkers are increased in hypertensive patients
with periodontitis. Over the years, various researches have been performed to evaluate the involvement of periodontitis in the
initiation and progression of hypertension. Many cross-sectional studies documented an association between hypertension and
periodontitis.However,morewell-designed prospective population trials need to be carried out to ascertain the role of periodontitis
in hypertension.