Mean HRQOL scores were decreased 2.56 in the laugh- ter therapy group and 2.22 in the control group, which were not significant (P = 0.347 and P = 0.392, respec- tively). In the laughter therapy group, the MH, VT and GH scales were significantly increased (7.00, 8.85 and 6.50, respectively). In the control group, however, there were no significant differences in all HRQOL scales