Abstract
Lupus nephritis is a common complication of systemic lupus erythematosus (SLE), an autoimmune disease
that targets organs such as the kidney. It affects more than 60% of lupus patients and is associated with
significant morbidity and mortality. The clinical manifestation of the disease is unpredictable, ranging form
no symptoms to serious proteinuria progressing to acute renal failure. Understanding the disease and its
progress is vital for nurses to provide optimal care and education to the patient. This paper will discuss the
mechanisms of disease and its clinical manifestations, classifications, diagnosis and management