Three new cases of cryptococcosis with positive culture for C. neoformans were diagnosed during the study period.
All had a positive LFA (3 serum and two CSF samples) with LA titration ranging from ½ to 1/256. Another patient had a
previous history of cryptococcosis, and two of his sera were found positive with the LFA and the EIA test with a
confirmation by the LA test (titration at 1/512 in both cases).
Two HIV-positive patients without any clinical symptoms were tested positive for cryptococcal antigen in serum
with the LFA. LA titration was at ½ and 1/32, respectively.
For both patients, similar results were obtained from control sera drawn one week and one month later, in one
case and 9 days later in the second one