A limited amount of data has indicated that TCM herbs could relieve anthracycline-induced cardiotoxicity. Choi et al. showed that licorice extracts had a protective effect against doxorubicin-induced cardiac apoptosis in vitro. The therapeutic effects on anthracycline-induced CHF were likely related to the major ingredient of ZGCT, Radix Glycyrrhizae preparata. After 2 months of treatment with modified ZGCT formulas, the patient’s exertional dyspnea and fragility subsided, consistent with the regression of pulmonary edema. This experience suggested that TCM could be used to treat the progression of congestive heart failure secondary to chemotherapy; in this case, strategies to prevent or reduce doxorubicin cardiotoxicity were not manipulated.