Abstract: Hundred raw milk and sixty milk product samples namely Gulabjamun, Mawa and Dahi were randomly collected from different localities/sources of Tandojam for the isolation of E.coli, a notorious contaminant. All the samples were inoculated on different bacteriological media and a number of biochemical tests were performed for the confirmation of the isolate. The results revealed that out of 1OO milk samples 57% showed growth of E. coli. The highest number of milk samples contaminated with E. coli were recorded in milk samples obtained from milk vending shops and houses. Among the 60 milk product samples 31(51.66%) showed growth of E.coli, the highest rate of contamination was found in Mawa/Khoa samples.