Study parameters and data analysis Acne severity Number of AV lesions in photos of the face, upper chest and back were calculated, classified as inflamed (papules & pustules) and non-inflamed (comedos) lesions. To evaluate the efficacy of the treatment, we define the success as 20% reduction in numbers of AV lesion. The changes in acne severity (mild, moderate or severe AV) were assessed according to Lehman’s criteria with a scoring system to measure the severity of AV14 in accordance with photographic technique scores