This study analysed human patch tests conducted from May 2001 to December 2012 with 4606 materials of proto- type or finished cosmetic products on 7440 normal Korean women aged 1860 years. The tested products were patched under occlu- sion for 24 or 48 h, and skin tolerance was assessed twice at 30 min and 24 h after patch removal using a 5-step scale accord- ing to the CTFA guidelines