For the treatment of Wistar rats infected with the yeast Candida albicans, the solution of AmB, solubilized at 10–4 M in buffer acetate/acetic acid (100 mM) pH 5.4, 1 mg/kg every 48 hours, does not prove effective. The blood is negative (0 cfu/mL) in only 50% of rats after 9 days. However, in the remaining 50%, the rate of yeast is very low (5 × 103 cfu/mL) to start inoculum (1.7 × 105).