Production of bioactive metabolites by microorganisms are often growth-associated, and it has been reported that most
bioactive production takes place upon cessation of exponential growth (Carvalho et al.2010). In this study,Lactobacillus casei BT 1268,L. rhamnosus FTDC 8313,L.gasseri FTDC 8131,B .animalis subsp. lactis BB 12 and B. longum BL 8643 showed the highest growth among the 15 strains studied, and thus were selected for evaluation on bioactive and inhibitive dermal compounds during growth in the stationary phase.