FAs are lipophilic compounds that bind different types of car- riers and receptors/transporters. Isabelle Niot and her colleagues report the existence in the intestine of various lipid binding pro- teins (LBP) and discuss the physiological contribution of each of these proteins in the absorption of long-chain FAs together with their reassembly into chylomicrons, the triglyceride-rich lipopro- teins that contribute primarily to the serum lipid level. In addition, the role of lipid droplets in chylomicron synthesis and in other pre- viously unsuspected functions is stressed by Sylvie Demignot and her collaborators in an elegant review article. In contrast, high- density lipoproteins are triglyceride-poor particles that exert cardi- oprotective effects highlighted by Maïga et al. in this issue. Michel