A recent questionnaire survey on the use of
throat lozenge formulations in healthy volunteers
confirmed the anaesthetic effect of AMC/DCBA
lozenges, in particular, lozenges containing
lidocaine and hexylresorcinol. Higher
concentrations of the active ingredients resulted in
a greater numbing effect with lozenges that
contained hexylresorcinol and lidocaine (14).
This article describes the first randomised
study comparing the analgesic efficacy of two
lozenges one containing AMC/DCBA and
lidocaine and one containing hexylresorcinol
versus placebo in patients with acute sore throat
due to an upper respiratory tract infection (URTI).
The aim was to characterise the speed and
duration of analgesic efficacy of the AMC/DCBA
+ lidocaine lozenges and hexylresorcinol
lozenges, compared with a placebo lozenge in this
patient population