Sodium humate is the salt of humic acid and can be extracted from Leonardite. Due to its low price and excellent chemical and electrochemical properties, sodium humate has been used for a variety of different applications. For instance, sodium humate has been used as a scavenger of toxic metals in wastewater treatment, as a mud adjuster in oil drilling and as an additive in the food and fertilizer industries. Moreover, the results of the present study indicate that sodium humate can be used as a pyrite depressant in the separation of chalcopyrite and pyrite at pH values lower than usual for pyrite depression, and the amount of CaO added to the concentrate can be significantly reduced