ysical exam may reveal obvious defects in the eyelids and are typically seen at or soon after birth. Eyelid coloboma, however, can be minimal and not discovered until later in life. (Figure 2)
Lens coloboma is seen as flattening of the equator of the lens in an area of absence of zonular fibers. This is best visualized in a dilated eye and may be incidental. (Figure 3)
Anteriorly located coloboma often appears as a defect in the iris tissue. They are classified as “typical” if found in the inferonasal quadrant of the affected structure and “atypical” if found elsewhere. Cornea, ciliary body and zonules may also be involved. (Figure 4)