Patients were most commonly Caucasian (44.2%) or African American (43.4%) men with a median
age of 28 years at HIV diagnosis. HSV-2 seroprevalence at HIV diagnosis decreased from the period of
1996–2004 (48.8%) to 2005–2012 (30.1%; P < 0.01). Odds of HSV-2 seropositivity was significantly greater
for non-Caucasians (OR 2.19, 95% CI 1.33–3.60) and for HIV diagnosis between 1996 and 2004 (OR 2.06,
95% CI 1.29–3.27)