Recent developments in somatic cell nuclear transfer technology
has allowed for the production of clones of several large animal
species [5,6]. In particular, this technology has led to the ability to
produce cloned animals from the genome of somatic cells
maintained in tissue culture. The ability to introduce changes to
the genome of cultured somatic cells paves a way to create specific
genetic modifications that are important not only for trait
improvement but also to study the pathogenesis of disease. The
use of SCNT technology has already contributed to the creation of
genetically engineered swine [7–9].