Results: The mean bodyweight at the start of the initial study was 100.6 ± 14.7 kg. At six months
it was 89.2 ± 14.3 kg. From 6 to 22 months, mean bodyweight had increased by 2.7 ± 4.2 kg to an
average of 92.0 ± 14.0 kg. At 44 months average weight has increased from baseline g to 93.1 ±
14.5 kg. Of the sixteen patients, five have retained or reduced bodyweight since the 22 month point
and all but one have lower weight at 44 months than at start. The initial mean HbA1c was 8.0 ±
1.5%. After 6, 12 and 22 months, HbA1c was 6.1 ± 1.0%, 7.0 ± 1.3% and 6.9 ± 1.1% respectively.
After 44 months mean HbA1c is 6.8 ± 1.3%.
Of the 23 patients who have used a low-carbohydrate diet and for whom we have long-term data,
two have suffered a cardiovascular event while four of the six controls who never changed diet
have suffered several cardiovascular events.