After mice were treated with PBS 1 h before giving indomethacin at 20 mg/kgBW mucus content was significantly decreased when compared to normal mice. In contrast, SCC 100– 500 and omeprazole 100 mg/kgBW significantly increased mucus levels compared to indomethacin treated group which indicated the defensive system of SCC extract and
omeprazole against indomethacin induced gastric ulcer.
However, we found that vitamin C treated group showed no difference of mucus content compared to indomethacin treated alone group (Table 1).