Fermentation of seaweed to produce larval feed was developed using an in situ fermentor. Marine single cell detritus MSCD, a seaweed based fermented product is an ideal material for feeding shrimp larvae. This paper deals with the development of protocol for the preparation of MSCD using the fermentor. Enzymatic hydrolysis of the seaweed cell wall is a procedure used in many applications. It has been described for improving protein digestibility by removing anti-nutritional factors such as polysaccharides