Centella asiatica is reputed for its beneficial effects in various neurological disorders. The present investigation
was undertaken to evaluate the role of 70% hydro-ethanolic extract of Centella asiatica (CA) on generalized
anxiety disorder (GAD) in man. Hamilton’s Brief Psychiatric Rating Scale (BPRS) was used to screen the
subjects. Thirty-three participants (18 male and 15 female; average age 33 yrs) were medicated with the CA in
a fixed dose regime (500 mg/capsule, twice daily, after meal). They were thoroughly investigated using standard
questionnaires based on psychological rating scale at baseline (day 0), mid-term (day 30) and final (day 60).
The scale also includes a number of direct queries about current levels of experienced stress. The observations
revealed that, CA not only significantly (p