Tuberculosis in pregnancy is more likely to be seen in areas with a higher incidence of TB and in ethnic minority women. It should be suspected in women with these background risk factors in the presence of non-specific signs and symptoms and/or the presence of clinical features suggesting pulmonary or extrapulmonary disease. Tuberculin skin testing is a valuable screening test in pregnancy and should be carried out if latent TB is suspected. Chest X-ray with shielding is essential and safe in all TB suspects. Pregnancy does not affect the course of TB; however, delay in treatment or untreated TB increases maternal morbidities and has the potential to cause increased incidence of preterm labour and growth restriction and can be transmitted to the newborn. First-line antituberculous drugs such as isoniazid, rifampicin and ethambutol can be used safely in pregnancy and while breastfeeding. Co-infection with HIV increases maternal mortality rates. It is beyond the scope of this review to discuss MDR-TB and TB with HIV in cases of pregnancy.