Cloninger's model and the corresponding instruments of evaluation, the Tridimensional Personality Questionnaire (TPQ) and the Temperament and Character Inventory (TCI), have been widely applied to subjects affected by mood disorders (MOOD). However, studies comparing temperament and character dimensions between MOOD patients and healthy subjects (HS) have yielded contradictory results. Most studies have reported a higher HA in MOOD in general , while Bipolar Disorder (BP) seems to be characterized by higher scores in NS , RD and ST .