(3) Early rescue surfactant should be administered to previously untreated babies if there is evidence of RDS (A). Individual units need to develop protocols for when to intervene as RDS progresses depending on gestational age and prior treatment with antenatal steroids (D). Poractant alfa in an initial dose of 200 mg/kg is better than 100 mg/kg of poractant alfa or beractant for treatment of moderate to
severe RDS (B).