supporting the possibility
of a mechanism in reduction of wrinkles. Additionally,
niacinamide restores lowered epidermal barrier
function12 that may lead to the improvement of fine
lines or wrinkles. Tanno et al. reported that niacinamide
improves keratinization and increases the
synthesis of ceramides in human keratinocytes.13
Some studies indicate that niacinamide reduces
transepidermal water loss and improves horny layer
moisture in patients with sun-damaged skin,12
rosacea14 and atopic dermatitis