Peptic ulcer was the second commonest cause of bleeding in liver cirrhosis, following varices, and most frequent cause of NVUGIB. Many patients had risk factors associated with peptic ulcer disease. Twenty-seven percent were smokers, 63% were using aspirin or non-steroidal anti-inflammatory drugs and 5% were consuming alcohol. Sixteen percent had previous history of peptic ulcer. Gastric biopsies were not examined for Helicobacter pylori. In contrast to peptic ulcer disease in the general population, the pathogenic role of Helicobacter pylori in cirrhotic patients remains questionable and may not be a major risk factor for peptic ulcer disease in cirrhotic patients. [8] and [11] it was reported that the role of Helicobacter pylori infection seemed controversial in cirrhotic patients. 10 The benefit of Helicobacter pylori eradication in patients with cirrhosis and peptic ulcer disease has been questioned. [11] and [12] Furthermore, eradication of Helicobacter pylori in patients with cirrhosis does not effectively reduce the recurrence of peptic ulcers.10 The avoidance of peptic ulcer risk factors, and the early diagnosis and treatment of peptic ulcer when present in liver cirrhosis patients are important to prevent complications (bleeding and mortality).