Causes
Typically, an allergic response is not triggered the first time the body encounters the semen allergen (protein in the semen that causes an allergic reaction). In fact, some people can be repeatedly exposed to the allergen before an allergy develops. The first time or several times after the body is exposed to the allergen, the immune system becomes sensitized. During this process, the body's white blood cells develop immunoglobulin E (IgE) antibodies to the semen allergens.
Once sensitized, the antibodies quickly detect and bind to the semen allergens the next time they enter the body. These antibodies also trigger the release of chemicals, including histamine, which cause allergic symptoms such as hives, inflammation, and itchy skin, as well as anaphylaxis. Anaphylaxis is a severe allergic reaction that affects many body parts. Symptoms of anaphylaxis include low blood pressure, difficultly breathing, shock, and loss of consciousness. Symptoms can vary from mild to severe and may be life threatening without immediate treatmen