although knowledge about the effects of methylxanthines on inflammation is scarce, these compounds have shown to reduce allergic inflammation (Tilley, 2011). Thus, perhaps, the higher theobromine content in DFCP may be responsible for the reduction in IL-1b. However, the effects of DFCP on inflammation are not clear and should be investigated further as a decrease in antiinflammatory cytokine IL-10 was also observed.