It is generally agreed that respiratory support in VLBW infants must be conducted in such a way as to circumvent damage caused by pressure, volume or oxygen. Results of a meta-analysis conducted by Stevens et al. demonstrate that extubation after early surfactant therapy and subsequent respiratory assistance with nasal continuous positive airway pressure results in a lower incidence of BPD compared with selective surfactant therapy and subsequent mechanical ventilation [14]. Other authors have presented similar observations favoring less invasive methods of respiratory assistance and lower ventilation values [15,16]. Oxygen therapy and the subsequent action of its derivates (free radicals) has been proven to increase the incidence of BPD [17,18]. To prevent such complications, practical guidelines recommending lower blood oxygen saturation values for preterm babies have been introduced [19,20].