According to Dutch air accident investigators, the plane departed from Amsterdam's Schiphol Airport at 10:31 GMT (12:31 local time) on 17 July and was due to arrive at Kuala Lumpur International Airport at 22:10 GMT (06:10 local time).
In its preliminary report, the Dutch Safety Board said the plane lost contact with air traffic control at 13:20 GMT, when it was about 50km from the Russia-Ukraine border.
Malaysia Airlines had initially said that the plane lost contact at 14:15 GMT.
Footage later emerged of the crash site in territory controlled by pro-Russian separatists, and witnesses spoke of dozens of bodies on the ground.