I'd look for nanotechnology to make revolutionary changes in medicine, communication, trasmportation, even more so than it already has. We will soon be able to build sophisticated machines on a very small scale that could, for example, clean out your arteries from the inside without invasive surgery, or deliver chemo or radation directly inside cancerous tissue. Just a few examples. Computers and communication devices will continue to get more powerful, and be able to do more, and this will make our lives both easier and less private