Chitosan, when applied to plant tissues, often agglutinate around the penetration sites and has two major effects. The first one is the isolation of the penetration site through the formation of a physical barrier preventing the pathogen from spreading and invading other healthy tissues. This phenomenon resembles the abscission zones often observed on leaves preventing several necrotrophic pathogens from spreading further. It is widely observed on potato tubers for example [79]. Around the isolated zones, often an elicitation of a hypersensitive response occur with the accumulation of H2O2 that helps in cells wall fortification and serve as an alert signal for other healthy parts of the plant. The second effect is due to the chitosan’ ability to bind various materials and initiate fast the wound healing process