There has been an increasing consumer demand for foods free or with low added synthetic
preservatives that could be toxic [1]. Concomitantly, consumers have also demanded for
wholesome and safe food with long shelf lives. These requirements press on the food industry
for progressive chemical preservatives removal and adoption of natural alternatives to obtain
safe food with long shelf lives [2]. Some plants demonstrate antimicrobial activity [3] with
application in the food industry as antibacterial and antifungal agents [4]. The spices can be
used safety of synthetic preservatives [5]. Although the primary purpose of spices is to impart
food flavor, the antimicrobial and antioxidant properties have also been exploited [6]. The
antimicrobial activity was documented and the interest continues to the present [7; 8] by the
increase of fungal resistance to classical drugs and the treatment costs. In spite the
introduction of new antifungal drugs, they are limited in number, so aromatic plants have
been widely used in folk medicine. It is known that most of their properties are due to their
volatile oils. Essential oils from many plants are known to the antifungal activity [9]. The
nutmeg (Myristica fragrans) is any of several species of trees in genus Myristica. The most
important commercial species is Myristica fragrans, an evergreen tree indigenous to the
Banda Islands in the Moluccas of Indonesia, or Spice Islands. Widely used as a food