Innovative chemistry learning material has been implemented in the teaching and learning activities. The influence of learning material to improve student’s achievements in chemistry has been investigated as summarized in Table 5. It has been observed that the students in the experimental groups are interested to use developed innovative chemistry materials. The results showed that student achievements in experimental classes (M = 83.0) is found higher than that in control class (M = 73.5), where both are significantly different. The phenomena where the students achievements in experimental class are all higher than that in control class have been observed in three target schools and for all four chapter of the chemistry subjects. Innovated chemistry learning materials are able to help the students to study chemistry. The contents of chemistry in an innovated learning material are adequate to be used as a source of knowledge that make the student improve in their competence on chemistry, and has meet the target criteria that are listed in national curriculum. The facilities in the learning material are able to help the students to learn chemistry by themselves. The scientific facilities that are integrated in learning materials are found very effective for scientific communication on teaching and learning activities. The example that are provided in learning materials are adequate to guided the students to learn and to solve chemistry problems related to chemistry topic. Sets of laboratory experiments that are integrated in the learning material (via e-book) could be viewed by the students, and it is able to help them to extend their knowledge and understanding related to a given theory in the chemistry material without doing the experiment in the laboratory by themselves. However, the students who are interetsed to do real experiment can use the material as it is provided with adequate intruction to do experiment in the laboratory accompany with laboratory data sheet for laboratory investigation.