Prevention of kidney disease for SLE patients 1) Anti-hypertensive: Patients with Class I and II lupus nephritis normally have good prognoses and very rarely require aggressive treatment for their renal disease. However, optimal blood pressure (BP) control with angiotensin-converting enzyme (ACE) inhibitors or angiotensin-receptor blockers (ARB) is necessary (Borchers, et al., 2012). Both these groups of drugs reduce intraglomerular pressure, lower systemic arterial BP, reduce proteinuria and, thus, delay the disease progression. A recent multi-ethnic US cohort study proved that the rate of renal involvement-free survival at 10 years is higher for patients treated with ACE inhibitors than those treated with non-ACE inhibitor group (Uchida & Nita, 2012; Griffin & Lightstone, 2013). Therefore, nursing staff should educate renal patients, particularly those with lupus nephritis on the importance of these medications (ACE-inhibitors or ARBs) and monitor their vital signs, especially BP with a goal of