Nowadays, many researchers have studied on the biosynthetic pathway to xanthones in plants in vivoly and in vitroly with markers (Diderot et al., 2006). Through biosynthesis, researchers can inter-relate the observed oxygen patterns of natural xanthones and correlate natural xanthones with recognized oxygenation patterns. There are two processes which involve in biosynthesis.
(i) Acetate polymalonic route
(ii) Mixed shikimate acetate pathway