base on the cytotoxic potential of a chemical substance to disrupt cell
plasma membranes and denatureseveral types of proteins
• measure the membrane damage by photometrically the leakage of
hemoglobin from freshly isolated red blood cells incubated with test
materials under standard conditions
• a validated alternative to the Draize eye irritation test for acute effects of
t i l f t typicalsurfactant- b d f l ti d i di tased formulationsand ingredients