The bacteriological test of patients with acne inversa
points to the lack of bacterial flora or mixed flora containing
Gram-positive and Gram-negative bacteria. In
deep biopsies of lesions, coagulase-negative staphylococcican
sometimes be found. Researchers suggest that
it indicates disorders of cellular innate immunity in relation
to the physiological flora, probably also in saccharomyces.
In patients with inverted acne, skin lesions hardly
ever cause fever, sepsis or lymphadenopathy. Laboratory
tests conclude accelerated OB, increased leukocytosis
and other markers of the chronic inflammatory process