We searched PUBMEDusing the keywords ‘scrub typhus’
or ‘O. tsutsugamushi’in any field. The search was restricted
to articles published in English within the last 15years
(1994-2009) as they would contain more recent data. We
screened all abstracts for relevance, i.e., data on clinical
manifestations and presentations, pathophysiology, and
prognosis (independent coding by three reviewers). Suitable
data was available in 112sources. Data sources included;
reviews published in core clinical journals, cohort studies,
interventional studies, clinical trials and cross sectional
analyses. Hundred and one papers were reviewed from a
selected 112(90.2%).