The characteristics of the study participants at each time point are provided in Table 2. At baseline, most participants were female, were non-Hispanic white, and did not live alone. On average, participants had a high school education and 2 chronic conditions. Only a few had significant cognitive impairment. About half of the participants met the criterion for prefrailty, while comparable proportions were classified as nonfrail and frail. Over time, as the cohort aged, the proportion of participants who were frail increased, while the proportions who were nonfrail or prefrail decreased. As shown in Figure 2, each of the frailty criteria was strongly associated with the probability of survival.